Molecule Details
| InChIKey | HVYYDLJKIQKWSE-XZOQPEGZSA-N |
|---|---|
| Compound Name | trans-(1R,2R)-2-[4-[3-[3-[(1-methylcyclopropyl)carbamoyl]-4-oxo-1,8-naphthyridin-1-yl]phenyl]phenyl]cyclopropane-1-carboxylic acid |
| Canonical SMILES | CC1(NC(=O)c2cn(-c3cccc(-c4ccc([C@@H]5C[C@H]5C(=O)O)cc4)c3)c3ncccc3c2=O)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 9.24 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 9.2 | IC50 | ChEMBL |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 9.2 | IC50 | ChEMBL |
| Q08493 | PDE4C | Homo sapiens | Human | PF18100 PF00233 | 9.2 | IC50 | ChEMBL |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 9.2 | IC50 | ChEMBL |