Molecule Details
| InChIKey | HVXFNUXEOUIQKE-IARZGTGTSA-N |
|---|---|
| Compound Name | (5S)-N-[(1S,2R)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropyl]-2-oxo-3-phenyloxazolidine-5-carboxamide |
| Canonical SMILES | CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@@H]1CN(c2ccccc2)C(=O)O1)S(=O)(=O)c1ccc(N)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 9.1 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9YQ12 | protease | Human immunodeficiency virus type 1 | Pathogen | PF00077 | 9.3 | Ki | ChEMBL;BindingDB |
| Q72874 | pol | Human immunodeficiency virus type 1 | Pathogen | PF00077 | 9.2 | Ki | ChEMBL |
| P03369 | gag-pol | Human immunodeficiency virus type 1 group M subtype B (isolate ARV2/SF2) | Pathogen | PF00540 PF19317 PF00552 PF02022 PF00075 PF00665 PF00077 PF00078 PF06815 PF06817 PF00098 | 8.9 | Ki | BindingDB |