Molecule Details
| InChIKey | HVROSOVHMGPEMN-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-[2-(5-chloro-2,3-dihydro-1H-inden-2-yl)ethyl]-4-pyridin-2-ylpiperazine |
| Canonical SMILES | Clc1ccc2c(c1)CC(CCN1CCN(c3ccccn3)CC1)C2 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.3 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P08908 | HTR1A | Homo sapiens | Human | PF00001 | 8.2 | Ki | ChEMBL;BindingDB |
| P21917 | DRD4 | Homo sapiens | Human | PF00001 | 7.4 | Ki | ChEMBL;BindingDB |
| P34969 | HTR7 | Homo sapiens | Human | PF00001 | 7.3 | Ki | ChEMBL;BindingDB |
| P28223 | HTR2A | Homo sapiens | Human | PF00001 | 7.0 | Ki | ChEMBL;BindingDB |
| P35462 | DRD3 | Homo sapiens | Human | PF00001 | 6.6 | Ki | ChEMBL;BindingDB |