Molecule Details
| InChIKey | HVHRHDHQHUAOQI-IBGZPJMESA-N |
|---|---|
| Compound Name | Aak1-IN-5 |
| Canonical SMILES | CC(C)C[C@](C)(N)COc1cnc(-c2ccnc(C(F)F)c2)cc1C(F)F |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.0 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q2M2I8 | AAK1 | Homo sapiens | Human | PF00069 | 8.9 | IC50 | ChEMBL;BindingDB |
| Q9NSY1 | BMP2K | Homo sapiens | Human | PF15282 PF00069 | 6.8 | IC50 | ChEMBL |
| Q9BUB5 | MKNK1 | Homo sapiens | Human | PF00069 | 6.6 | IC50 | ChEMBL |
| O14976 | GAK | Homo sapiens | Human | PF00069 PF10409 | 6.4 | IC50 | ChEMBL |
| Q9H1R3 | MYLK2 | Homo sapiens | Human | PF00069 | 6.3 | IC50 | ChEMBL |