Molecule Details
| InChIKey | HVEXJKQESNIDLM-KRWDZBQOSA-N |
|---|---|
| Compound Name | 5-[(5S)-5-(4-chlorophenyl)-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-3-yl]-3-methyl-2H-indazole |
| Canonical SMILES | Cc1n[nH]c2ccc(-c3nnc4n3[C@H](c3ccc(Cl)cc3)CC4)cc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 10 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.12 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (10)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P24863 | CCNC | Homo sapiens | Human | PF16899 PF00134 | 9.4 | IC50 | ChEMBL |
| P49336 | CDK8 | Homo sapiens | Human | PF00069 | 9.4 | IC50 | ChEMBL |
| P49760 | CLK2 | Homo sapiens | Human | PF00069 | 8.7 | Kd | ChEMBL |
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 8.7 | Kd | ChEMBL |
| P49840 | GSK3A | Homo sapiens | Human | PF00069 | 8.4 | Kd | ChEMBL |
| P49759 | CLK1 | Homo sapiens | Human | PF00069 | 7.8 | Kd | ChEMBL |
| Q9NRM7 | LATS2 | Homo sapiens | Human | PF00069 PF00433 | 7.8 | Kd | ChEMBL |
| Q9Y6M4 | CSNK1G3 | Homo sapiens | Human | PF12605 PF00069 | 7.4 | Kd | ChEMBL |
| Q8NEB9 | PIK3C3 | Homo sapiens | Human | PF00454 PF00792 PF00613 | 7.2 | Kd | ChEMBL |
| Q9Y463 | DYRK1B | Homo sapiens | Human | PF00069 | 6.5 | Kd | ChEMBL |