3-[[4-[2-(4-Fluorophenyl)-8-(2,2,2-trifluoroethoxy)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]amino]-2,2-dimethylpropan-1-ol

InChIKey	`HUXSWYWELGEQNC-UHFFFAOYSA-N`
Compound Name	3-[[4-[2-(4-Fluorophenyl)-8-(2,2,2-trifluoroethoxy)imidazo[1,2-a]pyrazin-3-yl]pyrimidin-2-yl]amino]-2,2-dimethylpropan-1-ol
Canonical SMILES	`CC(C)(CO)CNc1nccc(-c2c(-c3ccc(F)cc3)nc3c(OCC(F)(F)F)nccn23)n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	7.0
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P45984	MAPK9	Homo sapiens	Human	PF00069	8.2	Ki	ChEMBL
P48730	CSNK1D	Homo sapiens	Human	PF00069	8.0	Ki	ChEMBL
P45983	MAPK8	Homo sapiens	Human	PF00069	6.7	Ki	ChEMBL
P53667	LIMK1	Homo sapiens	Human	PF00412 PF00595 PF07714	6.1	Ki	ChEMBL
P48729	CSNK1A1	Homo sapiens	Human	PF00069	6.0	Ki	ChEMBL