InChIKey	HUPFGZXOMWLGNK-UHFFFAOYSA-N
Compound Name	Diflunisal
Canonical SMILES	O=C(O)c1cc(-c2ccc(F)cc2F)ccc1O
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.23
Source	ChEMBL;BindingDB;TTD_MultiTarget

DrugBank ID	DB00861
Drug Name	Diflunisal
CAS Number	22494-42-4
Groups	approved
ATC Codes	N02BA11
Description	Diflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though its mechanism of action has not been clearly established, most of...

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Categories: Agents causing hyperkalemia Agents that produce hypertension Analgesics Analgesics, Non-Narcotic Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) Antirheumatic Agents Benzene Derivatives Cyclooxygenase Inhibitors Drugs causing inadvertant photosensitivity Drugs that are Mainly Renally Excreted Enzyme Inhibitors Hydroxybenzoates Nephrotoxic agents Nervous System Non COX-2 selective NSAIDS OAT1/SLC22A6 inhibitors Other Nonsteroidal Anti-inflammatory Agents Peripheral Nervous System Agents Phenols Photosensitizing Agents Salicylates Salicylic Acid and Derivatives Sensory System Agents UGT1A9 Inhibitors

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Cross-references: BindingDB: 50240510 ChEBI: 39669 CHEMBL898 ChemSpider: 2951 Drugs Product Database (DPD): 2113 C01691 D00130 PDB: 1FL PharmGKB: PA449313 PubChem:3059 PubChem:46507807 RxCUI: 3393 Therapeutic Targets Database: DAP000152 Wikipedia: Diflunisal ZINC: ZINC000000020243