3-Amino-6-(4-{[2-(Dimethylamino)ethyl]sulfamoyl}phenyl)-N-Pyridin-3-Ylpyrazine-2-Carboxamide

InChIKey	`HULMMZPBCUBDJN-UHFFFAOYSA-N`
Compound Name	3-Amino-6-(4-{[2-(Dimethylamino)ethyl]sulfamoyl}phenyl)-N-Pyridin-3-Ylpyrazine-2-Carboxamide
Canonical SMILES	`CN(C)CCNS(=O)(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3cccnc3)n2)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	6.93
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P49841	GSK3B	Homo sapiens	Human	PF00069	7.7	Ki	ChEMBL;BindingDB
O96020	CCNE2	Homo sapiens	Human	PF02984 PF00134	6.7	Ki	ChEMBL
P24864	CCNE1	Homo sapiens	Human	PF02984 PF00134	6.7	Ki	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	6.7	Ki	ChEMBL