Molecule Details
| InChIKey | HUDQLWBKJOMXSZ-UHFFFAOYSA-N |
|---|---|
| Compound Name | AR-9281 |
| Canonical SMILES | CC(=O)N1CCC(NC(=O)NC23CC4CC(CC(C4)C2)C3)CC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.91 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB06345 |
|---|---|
| Drug Name | AR-9281 |
| CAS Number | 913548-29-5 |
| Groups | investigational |
| ATC Codes | nan |
| Description | AR-9281 inhibits soluble epoxide hydrolase. |
Categories: Amides Antihypertensive Agents Bridged-Ring Compounds Cardiovascular Agents Cycloparaffins Enzyme Inhibitors Epoxide Hydrolases, antagonists & inhibitors
Cross-references: BindingDB: 100423 CHEMBL436774 ChemSpider: 10173264 ZINC: ZINC000036330562
Target Activities (2)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P34913 | EPHX2 | Bifunctional epoxide hydrolase 2 | inhibitor | targets |