Molecule Details
| InChIKey | HTSNFXAICLXZMA-CYBMUJFWSA-N |
|---|---|
| Compound Name | (-)-3-Ppp |
| Canonical SMILES | CCCN1CCC[C@@H](c2cccc(O)c2)C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.24 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB20444 |
|---|---|
| Drug Name | Preclamol |
| CAS Number | 85966-89-8 |
| Groups | experimental |
| ATC Codes | nan |
| Description | Preclamol is a small molecule drug. Preclamol has a monoisotopic molecular weight of 219.16 Da. |
Categories: Anti-Dyskinesia Agents Anti-Parkinson Drugs Central Nervous System Agents Dopamine Agents Dopamine Agonists Neurotransmitter Agents
Cross-references: BindingDB: 50010617 CHEMBL7549 ZINC: ZINC000000402947
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P21917 | DRD4 | Homo sapiens | Human | PF00001 | 7.8 | Ki | ChEMBL;BindingDB |
| P14416 | DRD2 | Homo sapiens | Human | PF00001 | 7.7 | Ki | ChEMBL;BindingDB |
| P35462 | DRD3 | Homo sapiens | Human | PF00001 | 6.9 | Ki | ChEMBL;BindingDB |
| Q99720 | SIGMAR1 | Homo sapiens | Human | PF04622 | 6.6 | Ki | ChEMBL;BindingDB |
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P14416 | DRD2 | D(2) dopamine receptor | inhibitor | targets |