Molecule Details
| InChIKey | HTCPNTMZIFPYSY-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-(4-[2-[6-(2-chlorophenyl)-2-[[4-(diethylamino)butyl]amino]-7-oxo-7H,8H-pyrido[2,3-d]pyrimidin-8-yl]ethyl]phenyl)prop-2-enamide |
| Canonical SMILES | C=CC(=O)Nc1ccc(CCn2c(=O)c(-c3ccccc3Cl)cc3cnc(NCCCCN(CC)CC)nc32)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.94 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P21802 | FGFR2 | Homo sapiens | Human | PF07679 PF13927 PF07714 | 7.5 | IC50 | ChEMBL;BindingDB |
| P11362 | FGFR1 | Homo sapiens | Human | PF07679 PF00047 PF07714 | 7.4 | IC50 | ChEMBL;BindingDB |
| P22607 | FGFR3 | Homo sapiens | Human | PF21165 PF07679 PF13927 PF07714 | 6.6 | IC50 | ChEMBL;BindingDB |
| P22455 | FGFR4 | Homo sapiens | Human | PF07679 PF13927 PF07714 | 6.3 | IC50 | ChEMBL;BindingDB |