N-{[(4-fluorophenyl)carbamothioyl]amino}-2-hydroxy-2,2-diphenylacetamide

InChIKey	`HSKVRPZJBMXFDX-UHFFFAOYSA-N`
Compound Name	N-{[(4-fluorophenyl)carbamothioyl]amino}-2-hydroxy-2,2-diphenylacetamide
Canonical SMILES	`O=C(NNC(=S)Nc1ccc(F)cc1)C(O)(c1ccccc1)c1ccccc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	20
Pfam Stratification	Cross-Family
Avg pChEMBL	6.28
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q8IW41	MAPKAPK5	Homo sapiens	Human	PF00069	7.1	Ki	ChEMBL
Q14680	MELK	Homo sapiens	Human	PF02149 PF00069 PF21594	6.7	Ki	ChEMBL
P30530	AXL	Homo sapiens	Human	PF00041 PF13927 PF07714	6.6	Ki	ChEMBL
Q13131	PRKAA1	Homo sapiens	Human	PF16579 PF21147 PF00069	6.6	Ki	ChEMBL
Q96SB4	SRPK1	Homo sapiens	Human	PF00069	6.4	Ki	ChEMBL
P31749	AKT1	Homo sapiens	Human	PF00169 PF00069 PF00433	6.3	Ki	ChEMBL
Q96GD4	AURKB	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
Q96PF2	TSSK2	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
O43293	DAPK3	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL
P11309	PIM1	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL
P51955	NEK2	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL
Q86V86	PIM3	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL
Q9Y4K4	MAP4K5	Homo sapiens	Human	PF00780 PF00069	6.2	Ki	ChEMBL
P49841	GSK3B	Homo sapiens	Human	PF00069	6.1	Ki	ChEMBL
Q9H4B4	PLK3	Homo sapiens	Human	PF00069 PF00659	6.1	Ki	ChEMBL
Q9HAZ1	CLK4	Homo sapiens	Human	PF00069	6.1	Ki	ChEMBL
P04626	ERBB2	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	6.0	Ki	ChEMBL
P31751	AKT2	Homo sapiens	Human	PF00169 PF00069 PF00433	6.0	Ki	ChEMBL
P41743	PRKCI	Homo sapiens	Human	PF00130 PF00564 PF00069 PF00433	6.0	Ki	ChEMBL
Q00535	CDK5	Homo sapiens	Human	PF00069	6.0	Ki	ChEMBL