Molecule Details
InChIKeyHSIBGVUMFOSJPD-CFDPKNGZSA-N
Compound NameIbogaine
Canonical SMILESCC[C@H]1C[C@@H]2C[C@H]3c4[nH]c5ccc(OC)cc5c4CC[N@@](C2)[C@@H]13
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL6.44
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
Q5BJF2 TMEM97 Homo sapiens Human PF05241 7.0 Ki ChEMBL;BindingDB
P30926 CHRNB4 Homo sapiens Human PF02931 PF02932 6.7 IC50 ChEMBL
P32297 CHRNA3 Homo sapiens Human PF02931 PF02932 6.7 IC50 ChEMBL
P31645 SLC6A4 Homo sapiens Human PF03491 PF00209 6.3 Ki ChEMBL;BindingDB
P17787 CHRNB2 Homo sapiens Human PF02931 PF02932 6.0 IC50 ChEMBL
P43681 CHRNA4 Homo sapiens Human PF02931 PF02932 6.0 IC50 ChEMBL