Molecule Details
| InChIKey | HSHVHNIOQTZSOQ-UHFFFAOYSA-N |
|---|---|
| Compound Name | Cra_10656 |
| Canonical SMILES | CC(C)COc1cccc(-c2nc3ccc(C(N)=[NH2+])cc3[nH]2)c1[O-] |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.29 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB04470 |
|---|---|
| Drug Name | CRA_10656 |
| CAS Number | nan |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Cross-references: BindingDB: 50115857 CHEMBL64676 ChemSpider: 20138879 PDB: 656 PubChem:6119063 PubChem:46506984 ZINC: ZINC000002047593
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00749 | PLAU | Homo sapiens | Human | PF00051 PF00089 | 6.6 | Ki | ChEMBL;BindingDB |
| P00742 | F10 | Homo sapiens | Human | PF00008 PF14670 PF00594 PF00089 | 6.4 | Ki | BindingDB |
| P00734 | F2 | Homo sapiens | Human | PF00594 PF00051 PF09396 PF00089 | 6.3 | Ki | BindingDB |
| P00747 | PLG | Homo sapiens | Human | PF00051 PF00024 PF00089 | 6.2 | Ki | BindingDB |
| P00750 | PLAT | Homo sapiens | Human | PF00008 PF00039 PF00051 PF00089 | 6.0 | Ki | ChEMBL;BindingDB |
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P07477 | PRSS1 | Serine protease 1 | binder | targets |