Molecule Details
| InChIKey | HSHATGMVTYSDEB-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-[1-(4-Chlorophenyl)sulfonyl-6-(3-fluorophenyl)piperidin-2-yl]propan-2-yl 4-piperidin-1-ylpiperidine-1-carboxylate |
| Canonical SMILES | CC(C)(OC(=O)N1CCC(N2CCCCC2)CC1)C1CCCC(c2cccc(F)c2)N1S(=O)(=O)c1ccc(Cl)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.36 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P49768 | PSEN1 | Homo sapiens | Human | PF01080 | 8.4 | IC50 | ChEMBL;BindingDB |
| P49810 | PSEN2 | Homo sapiens | Human | PF01080 | 8.4 | IC50 | ChEMBL |
| Q8WW43 | APH1B | Homo sapiens | Human | PF06105 | 8.4 | IC50 | ChEMBL |
| Q92542 | NCSTN | Homo sapiens | Human | PF18266 PF05450 | 8.4 | IC50 | ChEMBL |
| Q96BI3 | APH1A | Homo sapiens | Human | PF06105 | 8.4 | IC50 | ChEMBL |
| Q9NZ42 | PSENEN | Homo sapiens | Human | PF10251 | 8.4 | IC50 | ChEMBL |