Molecule Details
| InChIKey | HPWBHQIUIBFTQC-UHFFFAOYSA-N |
|---|---|
| Compound Name | 6-(4-(4-(4-chlorophenyl)piperidin-4-yl)phenyl)-9H-purine |
| Canonical SMILES | Clc1ccc(C2(c3ccc(-c4ncnc5[nH]cnc45)cc3)CCNCC2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.54 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB07856 |
|---|---|
| Drug Name | 6-{4-[4-(4-CHLOROPHENYL)PIPERIDIN-4-YL]PHENYL}-9H-PURINE |
| CAS Number | nan |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Cross-references: BindingDB: 16232 CHEMBL228133 ChemSpider: 17279546 PDB: GVK PubChem:16122633 PubChem:99444327 ZINC: ZINC000014961053
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P31751 | AKT2 | Homo sapiens | Human | PF00169 PF00069 PF00433 | 7.7 | IC50 | ChEMBL;BindingDB |
| P17612 | PRKACA | Homo sapiens | Human | PF00069 | 7.5 | IC50 | ChEMBL |
| P22612 | PRKACG | Homo sapiens | Human | PF00069 | 7.5 | IC50 | ChEMBL |
| P22694 | PRKACB | Homo sapiens | Human | PF00069 | 7.5 | IC50 | ChEMBL |