Molecule Details
InChIKeyHPPQGIFLKZFURI-UHFFFAOYSA-N
Compound Name8-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperidin-3-yl]-propyl}-3-phenyl-2,3,8-triaza-spiro[4.5]decan-1-one
Canonical SMILESO=C(c1ccccc1)N1CCCC(CCCN2CCC3(CC2)CN(c2ccccc2)NC3=O)(c2ccc(Cl)c(Cl)c2)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.48
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P29371 TACR3 Homo sapiens Human PF00001 8.2 IC50 ChEMBL;BindingDB
P21452 TACR2 Homo sapiens Human PF00001 7.3 IC50 ChEMBL;BindingDB
P25103 TACR1 Homo sapiens Human PF00001 7.0 IC50 ChEMBL;BindingDB