Molecule Details
InChIKeyHOWBDMROKCOABA-AREMUKBSSA-N
Compound Nameethyl 3-[3-cyano-4-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]propoxy]phenyl]propanoate
Canonical SMILESCCOC(=O)CCc1ccc(OC[C@H](O)CNC(C)(C)Cc2ccc3ccccc3c2)c(C#N)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL8.2
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P41180 CASR Homo sapiens Human PF00003 PF01094 PF07562 10.5 IC50 ChEMBL;BindingDB
Q12809 KCNH2 Homo sapiens Human PF00027 PF00520 PF13426 8.8 IC50 ChEMBL;BindingDB
P10635 CYP2D6 Homo sapiens Human PF00067 8.5 IC50 ChEMBL;BindingDB
P07550 ADRB2 Homo sapiens Human PF00001 7.8 IC50 ChEMBL;BindingDB
P23975 SLC6A2 Homo sapiens Human PF00209 7.4 IC50 ChEMBL;BindingDB
Q01959 SLC6A3 Homo sapiens Human PF00209 7.2 IC50 ChEMBL;BindingDB
P31645 SLC6A4 Homo sapiens Human PF03491 PF00209 7.1 IC50 ChEMBL;BindingDB