Molecule Details
InChIKeyHOBMVEVXDIOMDM-UHFFFAOYSA-N
Compound Name3-Phenyl-3-[(6-pyridin-4-yl-1,3-benzothiazol-2-yl)amino]propan-1-ol
Canonical SMILESOCCC(Nc1nc2ccc(-c3ccncc3)cc2s1)c1ccccc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)18
Pfam Stratification Homologous
Avg pChEMBL6.38
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (18)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 7.7 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 7.1 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.9 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.9 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.5 Ki ChEMBL
P31749 AKT1 Homo sapiens Human PF00169 PF00069 PF00433 6.4 Ki ChEMBL
Q8NE63 HIPK4 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P05129 PRKCG Homo sapiens Human PF00130 PF00168 PF00069 PF00433 6.3 Ki ChEMBL
P31751 AKT2 Homo sapiens Human PF00169 PF00069 PF00433 6.2 Ki ChEMBL
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 6.2 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.1 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.1 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.0 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9HBY8 SGK2 Homo sapiens Human PF00069 PF00433 6.0 Ki ChEMBL
Q9HCP0 CSNK1G1 Homo sapiens Human PF12605 PF00069 6.0 Ki ChEMBL