Molecule Details
InChIKeyHNIDDGUBRPIXPG-SECBINFHSA-N
Compound Name2-[[(3R)-3-aminopyrrolidin-1-yl]methyl]-8-bromo-3H-[1]benzofuro[3,2-d]pyrimidin-4-one
Canonical SMILESN[C@@H]1CCN(Cc2nc3c(oc4ccc(Br)cc43)c(=O)[nH]2)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL7.01
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P11309 PIM1 Homo sapiens Human PF00069 8.2 IC50 ChEMBL;BindingDB
Q86V86 PIM3 Homo sapiens Human PF00069 8.2 IC50 ChEMBL;BindingDB
Q9P1W9 PIM2 Homo sapiens Human PF00069 7.1 IC50 ChEMBL;BindingDB
O00311 CDC7 Homo sapiens Human PF00069 6.7 IC50 ChEMBL;BindingDB
P19784 CSNK2A2 Homo sapiens Human PF00069 6.3 IC50 ChEMBL
P67870 CSNK2B Homo sapiens Human PF01214 6.3 IC50 ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 6.3 IC50 ChEMBL