Molecule Details
| InChIKey | HNHUNRACMOTTER-UHFFFAOYSA-N |
|---|---|
| Compound Name | 6-cyclopropyl-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-1-propan-2-ylpyrazolo[3,4-b]pyridine-4-carboxamide |
| Canonical SMILES | Cc1cc(C)c(CNC(=O)c2cc(C3CC3)nc3c2cnn3C(C)C)c(O)n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.7 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O75530 | EED | Homo sapiens | Human | PF00400 | 6.8 | Ki | ChEMBL |
| Q09028 | RBBP4 | Homo sapiens | Human | PF12265 PF00400 | 6.8 | Ki | ChEMBL |
| Q15022 | SUZ12 | Homo sapiens | Human | PF09733 PF23320 | 6.8 | Ki | ChEMBL |
| Q16576 | RBBP7 | Homo sapiens | Human | PF12265 PF00400 | 6.8 | Ki | ChEMBL |
| Q15910 | EZH2 | Homo sapiens | Human | PF21358 PF11616 PF18118 PF18264 PF00856 | 6.2 | Ki | ChEMBL;BindingDB |