beta-Sulfone piperidine hydroxamate, 2c

InChIKey	`HNEDFPGSHTUVKZ-UHFFFAOYSA-N`
Compound Name	beta-Sulfone piperidine hydroxamate, 2c
Canonical SMILES	`CC#CCOc1ccc(S(=O)(=O)CC2(C(=O)NO)CCN(C(=O)c3ccccc3)CC2)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	7
Pfam Stratification	Cross-Family
Avg pChEMBL	7.15
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P78536	ADAM17	Homo sapiens	Human	PF16698 PF00200 PF13574	9.0	IC50	ChEMBL;BindingDB
P08253	MMP2	Homo sapiens	Human	PF00040 PF00045 PF00413	7.2	pIC50	TTD_MultiTarget
P45452	MMP13	Homo sapiens	Human	PF00045 PF00413 PF01471	7.2	IC50	ChEMBL;BindingDB
Q9ULZ9	MMP17	Homo sapiens	Human	PF00045 PF00413 PF01471	6.8	pIC50	TTD_MultiTarget
P14780	MMP9	Homo sapiens	Human	PF00040 PF00045 PF00413	6.3	IC50	ChEMBL;BindingDB
P50281	MMP14	Homo sapiens	Human	PF11857 PF00045 PF00413 PF01471	6.3	IC50	ChEMBL;BindingDB
P18843	nadE	Escherichia coli (strain K12)	Pathogen	PF02540	7.2	pIC50	TTD_MultiTarget