Molecule Details
InChIKeyHMKKDSBJGMESJD-UHFFFAOYSA-N
Compound Name2-(Pyridin-4-yl)-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ol
Canonical SMILESO=c1[nH]c2sc3c(c2c2nc(-c4ccncc4)nn12)CCCC3
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Homologous
Avg pChEMBL7.05
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
O00311 CDC7 Homo sapiens Human PF00069 7.9 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 7.5 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 7.4 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 7.2 Ki ChEMBL
Q86V86 PIM3 Homo sapiens Human PF00069 7.2 Ki ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 7.0 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.9 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.3 Ki ChEMBL