Molecule Details
| InChIKey | HMDHSUIMQILHRP-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1''-(2,4-difluorophenethyl)spiro[3,4-dihydro-2H-chromene-2,4''-(hexahydropyridine)] |
| Canonical SMILES | Fc1ccc(CCN2CCC3(CCc4ccccc4O3)CC2)c(F)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.01 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P28223 | HTR2A | Homo sapiens | Human | PF00001 | 8.6 | Ki | ChEMBL;BindingDB |
| Q12809 | KCNH2 | Homo sapiens | Human | PF00027 PF00520 PF13426 | 7.0 | Ki | ChEMBL;BindingDB |
| P28335 | HTR2C | Homo sapiens | Human | PF00001 | 6.3 | Ki | ChEMBL;BindingDB |
| P14416 | DRD2 | Homo sapiens | Human | PF00001 | 6.1 | Ki | ChEMBL;BindingDB |