Molecule Details
InChIKeyHMBDNAGIIDHKKM-UHFFFAOYSA-N
Compound Name6-[6-(4-Fluorophenyl)imidazo[2,1-b][1,3]thiazol-5-yl]-1-propan-2-ylsulfonylbenzimidazol-2-amine
Canonical SMILESCC(C)S(=O)(=O)n1c(N)nc2ccc(-c3c(-c4ccc(F)cc4)nc4sccn34)cc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.92
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P45984 MAPK9 Homo sapiens Human PF00069 7.7 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 7.6 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 7.3 Ki ChEMBL
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 7.2 Ki ChEMBL
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 7.1 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.3 Ki ChEMBL
P04626 ERBB2 Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 6.2 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.0 Ki ChEMBL