Molecule Details
| InChIKey | HKZQRKPXNBQUSQ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1,3-Dibutyl-7-(3,4-dimethoxyphenyl)sulfonylpurine-2,6-dione |
| Canonical SMILES | CCCCn1c(=O)c2c(ncn2S(=O)(=O)c2ccc(OC)c(OC)c2)n(CCCC)c1=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.92 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 8.9 | IC50 | ChEMBL |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 8.9 | IC50 | ChEMBL;BindingDB |
| Q08493 | PDE4C | Homo sapiens | Human | PF18100 PF00233 | 8.9 | IC50 | ChEMBL |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 8.9 | IC50 | ChEMBL |