Molecule Details
InChIKeyHKSWAIDHHZHZTD-UHFFFAOYSA-N
Compound NameUS10072034, Example 3
Canonical SMILESCOc1cc(Nc2cc(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)cc(NS(C)(=O)=O)c4OC)c4ccccc34)ccn2)cc(OCCOCCOCC(=O)O)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL7.75
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P01375 TNF Homo sapiens Human PF00229 8.0 IC50 ChEMBL;BindingDB
P43405 SYK Homo sapiens Human PF07714 PF00017 7.9 IC50 ChEMBL;BindingDB
P10145 CXCL8 Homo sapiens Human PF00048 7.8 IC50 ChEMBL;BindingDB
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 7.7 IC50 ChEMBL;BindingDB
P28223 HTR2A Homo sapiens Human PF00001 7.6 IC50 BindingDB
P15260 IFNGR1 Homo sapiens Human PF07140 PF20634 PF01108 7.5 IC50 BindingDB