Molecule Details
InChIKeyHJYHJYGXRBYDIG-UHFFFAOYSA-N
Compound NameN-[5-(1-benzyltriazol-4-yl)-1H-indazol-3-yl]-2,5-difluorobenzamide
Canonical SMILESO=C(Nc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12)c1cc(F)ccc1F
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)23
Pfam Stratification Homologous
Avg pChEMBL7.06
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (23)
Target Gene Organism Category Pfam pChEMBL Type Source
P49841 GSK3B Homo sapiens Human PF00069 8.7 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 8.5 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 8.4 Ki ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 8.3 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 8.0 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 8.0 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 7.6 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 7.3 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 7.3 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 7.0 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.9 Ki ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.7 Ki ChEMBL
P34947 GRK5 Homo sapiens Human PF00069 PF00615 6.6 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.5 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 6.4 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 6.4 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q8IU85 CAMK1D Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9UHD2 TBK1 Homo sapiens Human PF00069 PF18394 PF18396 6.1 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 6.0 Ki ChEMBL