3-[3-bromo-5-[3-bromo-5-[3-[2-[3-bromo-4-[3-bromo-5-[3-[2-(3-bromo-4-hydroxyphenyl)ethylamino]-2-nitroso-3-oxopropyl]-2-hydroxyphenoxy]phenyl]ethylamino]-2-nitroso-3-oxopropyl]-2-hydroxyphenyl]-4-hydroxyphenyl]-N-[2-(3-bromo-4-hydroxyphenyl)ethyl]-2-nitrosopropanamide

InChIKey	`HJVFTUSVRMGBLM-UHFFFAOYSA-N`
Compound Name	3-[3-bromo-5-[3-bromo-5-[3-[2-[3-bromo-4-[3-bromo-5-[3-[2-(3-bromo-4-hydroxyphenyl)ethylamino]-2-nitroso-3-oxopropyl]-2-hydroxyphenoxy]phenyl]ethylamino]-2-nitroso-3-oxopropyl]-2-hydroxyphenyl]-4-hydroxyphenyl]-N-[2-(3-bromo-4-hydroxyphenyl)ethyl]-2-nitrosopropanamide
Canonical SMILES	`O=NC(Cc1cc(Br)c(O)c(Oc2ccc(CCNC(=O)C(Cc3cc(Br)c(O)c(-c4cc(CC(N=O)C(=O)NCCc5ccc(O)c(Br)c5)cc(Br)c4O)c3)N=O)cc2Br)c1)C(=O)NCCc1ccc(O)c(Br)c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	7
Pfam Stratification	Cross-Family
Avg pChEMBL	6.15
Source	BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	6.2	IC50	BindingDB
P35968	KDR	Homo sapiens	Human	PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854	6.2	IC50	BindingDB
Q02763	TEK	Homo sapiens	Human	PF00041 PF10430 PF07714	6.2	IC50	BindingDB
O00444	PLK4	Homo sapiens	Human	PF00069 PF18190 PF18409	6.2	IC50	BindingDB
P12931	SRC	Homo sapiens	Human	PF07714 PF00017 PF00018	6.2	IC50	BindingDB
P08581	MET	Homo sapiens	Human	PF07714 PF01437 PF01403 PF01833	6.1	IC50	BindingDB
P08069	IGF1R	Homo sapiens	Human	PF00757 PF07714 PF01030	6.0	IC50	BindingDB