Molecule Details
InChIKeyHJVDQPRJANOXIX-IVGNLCKYSA-N
Canonical SMILESO=C1Nc2cc(Br)ccc2/C1=C1Nc2ccccc2C/1=N\OCCN1CCNCC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL7.34
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 9.7 IC50 ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 8.5 IC50 ChEMBL;BindingDB
O14965 AURKA Homo sapiens Human PF00069 8.2 IC50 ChEMBL;BindingDB
P29597 TYK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 7.3 IC50 ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.8 IC50 ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.8 IC50 ChEMBL
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.7 IC50 ChEMBL;BindingDB
P06493 CDK1 Homo sapiens Human PF00069 6.6 IC50 ChEMBL;BindingDB
P14635 CCNB1 Homo sapiens Human PF02984 PF00134 6.6 IC50 ChEMBL
P23458 JAK1 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.2 IC50 ChEMBL