Molecule Details
InChIKeyHHSVICUMCOBRPT-UHFFFAOYSA-N
Compound Name3-(2-fluorophenyl)-N-methyl-2H-thieno[2,3-c]pyrazole-5-carboxamide
Canonical SMILESCNC(=O)c1cc2c(-c3ccccc3F)n[nH]c2s1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)33
Pfam Stratification Cross-Family
Avg pChEMBL6.37
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (33)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.9 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.9 Ki ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 6.8 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.8 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.7 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.7 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 6.7 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q86V86 PIM3 Homo sapiens Human PF00069 6.5 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P07332 FES Homo sapiens Human PF00611 PF07714 PF00017 6.4 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.4 Ki ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.4 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.4 Ki ChEMBL
P78368 CSNK1G2 Homo sapiens Human PF12605 PF00069 6.3 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P16591 FER Homo sapiens Human PF00611 PF07714 PF00017 6.2 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q8TDC3 BRSK1 Homo sapiens Human PF21122 PF00069 PF21115 6.2 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.2 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.1 Ki ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.1 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
Q8NE63 HIPK4 Homo sapiens Human PF00069 6.1 Ki ChEMBL
O15530 PDPK1 Homo sapiens Human PF14593 PF00069 6.0 Ki ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9Y6M4 CSNK1G3 Homo sapiens Human PF12605 PF00069 6.0 Ki ChEMBL