Molecule Details
InChIKeyHHCSNTXVZDWIGT-CMDGGOBGSA-N
Canonical SMILESCc1ccsc1C(=O)Nc1cc(CN2CCN(C(=O)CO)CC2)ccc1/C=C/c1n[nH]c2ccccc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL6.62
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB16637
Drug NameKW-2450 free base
CAS Number904899-25-8
Groups investigational
ATC Codes nan
Descriptionnan
Categories: Heterocyclic Compounds, Fused-Ring Pyrazoles
Cross-references: ChemSpider: 64853777
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
O14965 AURKA Homo sapiens Human PF00069 6.7 IC50 ChEMBL;BindingDB
Q96GD4 AURKB Homo sapiens Human PF00069 6.6 IC50 ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P06213 INSR Insulin receptor inhibitor targets
P08069 IGF1R Insulin-like growth factor 1 receptor inhibitor targets