Molecule Details
| InChIKey | HGVDHZBSSITLCT-JLJPHGGASA-N |
|---|---|
| Canonical SMILES | CN1CCc2nc(C(=O)N[C@@H]3C[C@@H](C(=O)N(C)C)CC[C@@H]3NC(=O)C(=O)Nc3ccc(Cl)cn3)sc2C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.71 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB09075 |
|---|---|
| Drug Name | Edoxaban |
| CAS Number | 480449-70-5 |
| Groups | approved investigational |
| ATC Codes | B01AF03 |
| Description | Edoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. By inhibiting factor Xa, a key protein in the coagulation cascade, edoxaban prevents the stepwise amplification of protein factors needed to form blood clots. ... |
Categories: Anticoagulants Antithrombins Blood and Blood Forming Organs Direct factor Xa inhibitors Drugs that are Mainly Renally Excreted Enzyme Inhibitors Factor Xa Inhibitors Hematologic Agents P-glycoprotein substrates Protease Inhibitors Serine Protease Inhibitors Sulfur Compounds
Cross-references: BindingDB: 50328731 ChEBI: 85973 CHEMBL1269025 ChemSpider: 8456212 Drugs Product Database (DPD): 22816 D09546 PharmGKB: PA166128806 PubChem:10280735 PubChem:310265005 RxCUI: 1599538 Wikipedia: Edoxaban ZINC: ZINC000043200832