Molecule Details
| InChIKey | HFIYFKUCCHWYDX-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-[(3-hydroxyphenyl)amino]-4-(2-methoxyphenyl)-2,5-dihydro-1H-pyrrole-2,5-dione |
| Canonical SMILES | COc1ccccc1C1=C(Nc2cccc(O)c2)C(=O)NC1=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.68 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9H2G2 | SLK | Homo sapiens | Human | PF00069 PF12474 | 7.2 | Ki | ChEMBL;BindingDB |
| P49840 | GSK3A | Homo sapiens | Human | PF00069 | 6.6 | IC50 | BindingDB |
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 6.6 | IC50 | ChEMBL;BindingDB |
| O94804 | STK10 | Homo sapiens | Human | PF00069 PF12474 | 6.3 | Ki | ChEMBL;BindingDB |