Molecule Details
| InChIKey | HFEKDTCAMMOLQP-RRKCRQDMSA-N |
|---|---|
| Compound Name | 5-Fluorodeoxyuridine monophosphate |
| Canonical SMILES | O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O)O2)cc1F |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.92 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB03761 |
|---|---|
| Drug Name | 5-fluoro-2'-deoxyuridine-5'-monophosphate |
| CAS Number | 134-46-3 |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Categories: Deoxyribonucleotides Deoxyuracil Nucleotides Nucleic Acids, Nucleotides, and Nucleosides Nucleotides Pyrimidine Nucleotides Pyrimidines Uracil Nucleotides
Cross-references: BindingDB: 50022238 ChEBI: 2129 CHEMBL886 ChemSpider: 8321 C04242 PDB: UFP PubChem:8642 PubChem:46508904 ZINC: ZINC000003875881
Target Activities (2)
DrugBank Target Actions (5)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| P00469 | thyA | Thymidylate synthase | binder | targets |
| P0A884 | thyA | Thymidylate synthase | binder | targets |
| P0CI79 | P0CI79 | Thymidylate synthase 1 | binder | targets |
| Q9WYT0 | Q9WYT0 | Flavin-dependent thymidylate synthase | binder | targets |
| P12461 | P12461 | Thymidylate synthase | inhibitor | targets |