3-(2-aminoquinazolin-6-yl)-1-(3-methoxyphenyl)-4-methylpyridin-2(1H)-one

InChIKey	`HFBUYDAMOBVPRQ-UHFFFAOYSA-N`
Compound Name	3-(2-aminoquinazolin-6-yl)-1-(3-methoxyphenyl)-4-methylpyridin-2(1H)-one
Canonical SMILES	`COc1cccc(-n2ccc(C)c(-c3ccc4nc(N)ncc4c3)c2=O)c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.78
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P10721	KIT	Homo sapiens	Human	PF00047 PF07714	7.4	IC50	ChEMBL;BindingDB
P12931	SRC	Homo sapiens	Human	PF07714 PF00017 PF00018	6.6	IC50	ChEMBL;BindingDB
P06239	LCK	Homo sapiens	Human	PF07714 PF00017 PF00018	6.4	IC50	ChEMBL;BindingDB