6-(4-amino-1-cyclopentyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-4H-chromen-4-one

InChIKey	`HFBMCRRHMRLGSA-UHFFFAOYSA-N`
Compound Name	6-(4-amino-1-cyclopentyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-4H-chromen-4-one
Canonical SMILES	`Nc1ncnc2c1c(-c1ccc3occc(=O)c3c1)nn2C1CCCC1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	7
Pfam Stratification	Cross-Family
Avg pChEMBL	6.77
Source	ChEMBL;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P78527	PRKDC	Homo sapiens	Human	PF20500 PF20502 PF08163 PF19704 PF02259 PF02260 PF00454	7.3	IC50	ChEMBL
P48736	PIK3CG	Homo sapiens	Human	PF00454 PF00792 PF00794 PF00613 PF19710	7.2	IC50	ChEMBL
O00329	PIK3CD	Homo sapiens	Human	PF00454 PF00792 PF02192 PF00794 PF00613	6.9	IC50	ChEMBL
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	6.8	pIC50	TTD_MultiTarget
P42336	PIK3CA	Homo sapiens	Human	PF00454 PF00792 PF02192 PF00794 PF00613	6.5	IC50	ChEMBL
P42345	MTOR	Homo sapiens	Human	PF02259 PF02260 PF08771 PF23593 PF11865 PF00454	6.4	pIC50	TTD_MultiTarget
P12931	SRC	Homo sapiens	Human	PF07714 PF00017 PF00018	6.3	IC50	ChEMBL