(7S,8R,11S)-11-N-[2-(dimethylamino)ethyl]-7-N-hydroxy-8-(2-methylpropyl)-9-oxo-2-oxa-10-azabicyclo[11.2.2]heptadeca-1(15),13,16-triene-7,11-dicarboxamide

InChIKey	`HEPINVNDBLHRTM-BDTNDASRSA-N`
Compound Name	(7S,8R,11S)-11-N-[2-(dimethylamino)ethyl]-7-N-hydroxy-8-(2-methylpropyl)-9-oxo-2-oxa-10-azabicyclo[11.2.2]heptadeca-1(15),13,16-triene-7,11-dicarboxamide
Canonical SMILES	`CC(C)C[C@H]1C(=O)N[C@H](C(=O)NCCN(C)C)Cc2ccc(cc2)OCCCC[C@@H]1C(=O)NO`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	6
Pfam Stratification	Cross-Family
Avg pChEMBL	8.17
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P09237	MMP7	Homo sapiens	Human	PF00413 PF01471	8.4	IC50	ChEMBL;BindingDB
P08253	MMP2	Homo sapiens	Human	PF00040 PF00045 PF00413	8.2	pIC50	TTD_MultiTarget
P03956	MMP1	Homo sapiens	Human	PF00045 PF00413 PF01471	8.2	IC50	ChEMBL;BindingDB
Q9ULZ9	MMP17	Homo sapiens	Human	PF00045 PF00413 PF01471	8.2	pIC50	TTD_MultiTarget
P08254	MMP3	Homo sapiens	Human	PF00045 PF00413 PF01471	7.9	IC50	ChEMBL;BindingDB
P18843	nadE	Escherichia coli (strain K12)	Pathogen	PF02540	8.2	pIC50	TTD_MultiTarget