Molecule Details
| InChIKey | HEESYZLXEJDLJI-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[(3,4-difluorophenyl)methyl]-6-(1H-pyrazol-4-yl)-1H-indole-3-carboxamide |
| Canonical SMILES | O=C(NCc1ccc(F)c(F)c1)c1c[nH]c2cc(-c3cn[nH]c3)ccc12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.11 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O75116 | ROCK2 | Homo sapiens | Human | PF25346 PF00069 PF08912 | 8.1 | IC50 | ChEMBL;BindingDB |
| Q13464 | ROCK1 | Homo sapiens | Human | PF25346 PF00069 PF08912 | 7.5 | IC50 | ChEMBL;BindingDB |
| P51817 | PRKX | Homo sapiens | Human | PF00069 | 6.7 | IC50 | BindingDB |
| P17612 | PRKACA | Homo sapiens | Human | PF00069 | 6.2 | IC50 | BindingDB |