Molecule Details
InChIKeyHDRLAVNNWSHSOA-UHFFFAOYSA-N
Compound NameN-(2-phenyl-8-prop-2-enylchromen-4-ylidene)hydroxylamine
Canonical SMILESC=CCc1cccc2c(=NO)cc(-c3ccccc3)oc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)19
Pfam Stratification Cross-Family
Avg pChEMBL6.43
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (19)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.6 Ki ChEMBL
P29376 LTK Homo sapiens Human PF12810 PF07714 7.3 Ki ChEMBL
Q5S007 LRRK2 Homo sapiens Human PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 6.8 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q9UM73 ALK Homo sapiens Human PF12810 PF00629 PF07714 6.6 Ki ChEMBL
P08581 MET Homo sapiens Human PF07714 PF01437 PF01403 PF01833 6.5 Ki ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P08069 IGF1R Homo sapiens Human PF00757 PF07714 PF01030 6.3 Ki ChEMBL
P49336 CDK8 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.3 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.2 Ki ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 6.2 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 6.2 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.1 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q14164 IKBKE Homo sapiens Human PF00069 PF18394 PF18396 6.1 Ki ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.1 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.0 Ki ChEMBL