HDKKEPJHRYPLPT-COXIKBTRSA-N

InChIKey	`HDKKEPJHRYPLPT-COXIKBTRSA-N`
Canonical SMILES	`CN1C(N)=N[C@](C)(c2cc(/C=C(\F)c3ccc(C#N)cn3)cc(F)c2F)CS1(=O)=O`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	8.17
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P56817	BACE1	Homo sapiens	Human	PF00026	8.5	IC50	ChEMBL;BindingDB
Q9Y5Z0	BACE2	Homo sapiens	Human	PF00026	7.8	IC50	ChEMBL;BindingDB