Molecule Details
| InChIKey | HBJUFAHIACMPFY-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-{[5-Fluoro-2-(phenylamino)pyrimidin-4-yl]amino}benzoic acid |
| Canonical SMILES | O=C(O)c1ccccc1Nc1nc(Nc2ccccc2)ncc1F |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.04 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O00311 | CDC7 | Homo sapiens | Human | PF00069 | 9.9 | Ki | ChEMBL |
| O14965 | AURKA | Homo sapiens | Human | PF00069 | 8.0 | IC50 | ChEMBL;BindingDB |
| Q9UM73 | ALK | Homo sapiens | Human | PF12810 PF00629 PF07714 | 7.2 | Ki | ChEMBL |
| P45983 | MAPK8 | Homo sapiens | Human | PF00069 | 7.1 | IC50 | ChEMBL;BindingDB |