Molecule Details
| InChIKey | HACQCGHVZICZSC-UHFFFAOYSA-N |
|---|---|
| Compound Name | AI-204/31750036 |
| Canonical SMILES | NS(=O)(=O)c1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1 |
| Clinical Status | Clinical Multi-Target |
| Targets (Human+Pathogen) | 7 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.34 |
| Source | ChEMBL;TTD_MultiTarget |
2D Structure
Activity Profile
Target Activities (7)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O43570 | CA12 | Homo sapiens | Human | PF00194 | 8.3 | Ki | ChEMBL |
| Q16790 | CA9 | Homo sapiens | Human | PF00194 | 7.2 | Ki | ChEMBL |
| P00918 | CA2 | Homo sapiens | Human | PF00194 | 6.1 | Ki | ChEMBL |
| P18505 | GABRB1 | Homo sapiens | Human | PF02931 PF02932 | 6.1 | pIC50 | TTD_MultiTarget |
| P9WPJ7 | mtcA1 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Pathogen | PF00484 | 8.3 | Ki | ChEMBL |
| Q6FTL6 | NCE103 | Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) | Pathogen | PF00484 | 8.2 | Ki | ChEMBL |
| P96878 | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) | Pathogen | PF00484 PF00916 | 7.2 | Ki | ChEMBL |