6-(3-Amino-1H-indazol-6-yl)-N4-(1-methylethyl)-2,4-pyrimidinediamine

InChIKey	`HABRRQSUPGOZTD-UHFFFAOYSA-N`
Compound Name	6-(3-Amino-1H-indazol-6-yl)-N4-(1-methylethyl)-2,4-pyrimidinediamine
Canonical SMILES	`CC(C)Nc1cc(-c2ccc3c(N)n[nH]c3c2)nc(N)n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.5
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O15530	PDPK1	Homo sapiens	Human	PF14593 PF00069	6.9	IC50	ChEMBL;BindingDB
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	6.3	pIC50	TTD_MultiTarget
P36897	TGFBR1	Homo sapiens	Human	PF01064 PF00069 PF08515	6.3	IC50	ChEMBL;BindingDB