Molecule Details
| InChIKey | GZHILIVJBZXHDF-HZHRSRAPSA-N |
|---|---|
| Compound Name | (2E)-3-(4-hydroxyphenyl)-2-phenylmethoxyimino-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)propanamide |
| Canonical SMILES | NS(=O)(=O)c1nnc(NC(=O)/C(Cc2ccc(O)cc2)=N/OCc2ccccc2)s1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.56 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P00918 | CA2 | Homo sapiens | Human | PF00194 | 9.1 | Ki | ChEMBL;BindingDB |
| Q16790 | CA9 | Homo sapiens | Human | PF00194 | 8.6 | Ki | ChEMBL;BindingDB |
| O43570 | CA12 | Homo sapiens | Human | PF00194 | 8.3 | Ki | ChEMBL;BindingDB |
| P00915 | CA1 | Homo sapiens | Human | PF00194 | 8.2 | Ki | ChEMBL;BindingDB |