Molecule Details
InChIKeyGZGLPBNOIFLLRE-UHFFFAOYSA-N
Compound NameAs-602868
Canonical SMILESCOc1cccc2nc(-c3cccs3)nc(NN3C(=O)C=C(C)C3=O)c12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL7.64
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P05412 JUN Homo sapiens Human PF00170 PF03957 8.1 IC50 ChEMBL;BindingDB
P19838 NFKB1 Homo sapiens Human PF12796 PF00531 PF16179 PF00554 8.1 IC50 ChEMBL
Q00653 NFKB2 Homo sapiens Human PF00023 PF12796 PF00531 PF16179 PF00554 8.1 IC50 ChEMBL
Q04206 RELA Homo sapiens Human PF16179 PF00554 8.1 IC50 ChEMBL
O14920 IKBKB Homo sapiens Human PF18397 PF12179 PF00069 7.2 IC50 ChEMBL;BindingDB
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.2 IC50 ChEMBL;BindingDB