Molecule Details
InChIKeyGYQLVKWGHKBDMP-UHFFFAOYSA-N
Compound Name3-{5-[(2-Fluorophenyl)amino]-1h-Indazol-1-Yl}-N-(3,4,5-Trimethoxyphenyl)benzamide
Canonical SMILESCOc1cc(NC(=O)c2cccc(-n3ncc4cc(Nc5ccccc5F)ccc43)c2)cc(OC)c1OC
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Homologous
Avg pChEMBL7.54
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P53779 MAPK10 Homo sapiens Human PF00069 8.1 IC50 ChEMBL;BindingDB
O15264 MAPK13 Homo sapiens Human PF00069 7.5 IC50 ChEMBL
P53778 MAPK12 Homo sapiens Human PF00069 7.5 IC50 ChEMBL
Q15759 MAPK11 Homo sapiens Human PF00069 7.5 IC50 ChEMBL
Q16539 MAPK14 Homo sapiens Human PF00069 7.5 IC50 ChEMBL;BindingDB
P45983 MAPK8 Homo sapiens Human PF00069 7.1 IC50 ChEMBL;BindingDB