Molecule Details
InChIKeyGXZFDXZCJALHRF-UHFFFAOYSA-N
Compound Name3-hydroxy-K252c
Canonical SMILESO=C1NCc2c1c1c3cc(O)ccc3[nH]c1c1[nH]c3ccccc3c21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Homologous
Avg pChEMBL6.82
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 8.2 IC50 ChEMBL;BindingDB
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 7.2 IC50 ChEMBL
O14920 IKBKB Homo sapiens Human PF18397 PF12179 PF00069 6.9 IC50 ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 6.5 IC50 ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.0 IC50 ChEMBL
Q99683 MAP3K5 Homo sapiens Human PF19039 PF20309 PF20302 PF13281 PF00069 6.0 IC50 ChEMBL