N-[[4-[[4-(3-ethyl-7-fluoro-2-methylbenzimidazol-5-yl)-5-fluoropyrimidin-2-yl]amino]phenyl]methyl]-N'-hydroxyoctanediamide

InChIKey	`GXMWQAXYHFYSNS-UHFFFAOYSA-N`
Compound Name	N-[[4-[[4-(3-ethyl-7-fluoro-2-methylbenzimidazol-5-yl)-5-fluoropyrimidin-2-yl]amino]phenyl]methyl]-N'-hydroxyoctanediamide
Canonical SMILES	`CCn1c(C)nc2c(F)cc(-c3nc(Nc4ccc(CNC(=O)CCCCCCC(=O)NO)cc4)ncc3F)cc21`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.05
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P01730	CD4	Homo sapiens	Human	PF05790 PF09191 PF00047 PF12104	8.9	IC50	ChEMBL
P23458	JAK1	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	7.7	IC50	ChEMBL
Q13547	HDAC1	Homo sapiens	Human	PF00850	7.6	IC50	ChEMBL