Molecule Details
InChIKeyGWEVPILGTKKVAZ-QGKFPQEJSA-N
Compound Nametert-butyl N-[2-[(5R,8S,11S)-5-methyl-6,9,13-trioxo-11-[(E)-4-sulfanylbut-1-enyl]-10-oxa-3,17-dithia-7,14,19,20-tetrazatricyclo[14.2.1.12,5]icosa-1(18),2(20),16(19)-trien-8-yl]ethyl]carbamate
Canonical SMILESCC(C)(C)OC(=O)NCC[C@@H]1NC(=O)[C@]2(C)CSC(=N2)c2csc(n2)CNC(=O)C[C@@H](/C=C/CCS)OC1=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL8.51
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13547 HDAC1 Homo sapiens Human PF00850 8.6 IC50 ChEMBL;BindingDB
Q92769 HDAC2 Homo sapiens Human PF00850 8.5 IC50 ChEMBL;BindingDB
O15379 HDAC3 Homo sapiens Human PF00850 8.4 IC50 ChEMBL;BindingDB